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eFORGE TF
TF-centric methylation array probe browser
About

The eFORGE TF application is an adjunct to the eFORGE EWAS analysis tool. This enables the exploration of DNase I tag (chromatin accessibility) signal surrounding methylation array probes and the calculation of significance of overlap with transcription factor binding sites from common TF databases.


Settings

Mode

View associations of transcription factors (TF) and footprints with an individual probe, or a summary of TF associations over all probes, with positional overlap of selected probes with associated TFs

Array

Sample

Padding

20
50
100
200
500

Padding (nt) around the probe genomic location

Smoothing

0
1
2
3
5

Smoothing window padding (nt)

Signal rendering

Display signal as bar chart ("density") or as line chart with cubic spline

TF overlaps

Display probe-specific or all transcription factor overlaps ("All" can increase query time)

Probe IDs

Probe IDs may be separated by commas or newline characters (max. 1000)